Optical and Electric Multifunctional CMOS Image Sensors for On-Chip Biosensing Applications
نویسندگان
چکیده
In this review, the concept, design, performance, and a functional demonstration of multifunctional complementary metal-oxide-semiconductor (CMOS) image sensors dedicated to on-chip biosensing applications are described. We developed a sensor architecture that allows flexible configuration of a sensing pixel array consisting of optical and electric sensing pixels, and designed multifunctional CMOS image sensors that can sense light intensity and electric potential or apply a voltage to an on-chip measurement target. We describe the sensors' architecture on the basis of the type of electric measurement or imaging functionalities.
منابع مشابه
An optical / potential / voltammetric multifunctional CMOS image sensor for on-chip biomolecular / neural analytical applications
Abstract We have developed an on-chip image sensor with target applications of on-chip biomolecular and neural imaging. The sensor pixel can sense not only intensity of incident light, but also on-chip electric potential. The light shield structure on the pixel circuit was used as a sensing electrode. Once the passivation layer on the sensing electrode was removed, one can perform on-chip volta...
متن کاملNew Method for Analysis of image sensor to produce and evaluate the image
In this paper, a new method for evaluating CMOS image sensors based on computer modeling and analysis is introduced. Image sensors are composed of different parts, each of which has a specific effect on image quality. Circuits of image sensors can be evaluated and analyzed using circuit simulators or theoretically, but these methods cannot help to produce the final image. In order to produce th...
متن کاملCMOS-Based Optoelectronic On-Chip Neural Interface Device
On-chip neural interface devices based on CMOS image sensor technology are proposed and demonstrated. The devices were designed with target applications to optogenetics in bioscience. Multifunctional CMOS image sensors equipped with an addressable on-chip electrode array were integrated with a functional interface chip that contained embedded GaInN light emitting diodes (LEDs) and electrodes to...
متن کاملNeural Monitoring With CMOS Image Sensors
Implantable image sensors have several biomedical applications due to their miniature size, light weight, and low power consumption achieved through sub-micron standard CMOS (Complementary Metal Oxide Semiconductor) technologies. The main applications are in specific cell labeling, neural activity detection, and biomedical imaging. In this paper the recent research studies on implantable CMOS i...
متن کاملVideo Processing Applications of High Speed Cmos Image Sensors
An important trend in the design of digital cameras is the integration of capture and processing onto a single CMOS chip. Although integrating the components of a digital camera system onto a single chip significantly reduces system size and power, it does not fully exploit the potential advantages of integration. We argue that a key advantage of integration is the ability to exploit the high s...
متن کامل